In the very early days of Guillain-Barré syndrome (GBS),
electrophysiological findings may be scarce but mostly required for the
substantiation of nerve and/or nerve root pathology. Abnormal F-waves,
absence of H reflexes, multiple A-waves and sural sparing are the bestknown
early findings of the disease. In this report, we present two cases
with GBS in whom the early electrophysiology revealed discharges
following the compound muscle action potentials. We propose that
these discharges may be another early sign of GBS and may reflect early
peripheral nerve demyelination and/or hyperexcitability.
Keywords: After-discharges, A-wave, demyelination, Guillain-Barré
syndrome, hyperexcitability