• Structured Interview of Psychosis Risk Syndromes (SIPS)
is a valid and reliable tool for diagnosing prodrome in
Turkish adolescents.
• SIPS is the first gold standard interview validated in the
Turkish language in this field.
• Adolescents with clinical high risk can be diagnosed with
prodromal syndromes with SIPS.
• SIPS-B that provides rapid screening in clinical conditions
is a four-item short version.
Introduction: The Structured Interview of Psychosis Risk Syndromes
(SIPS) was created to identify patients with Clinical High Risk for
psychosis (CHR). This study aimed i) to translate and validate the Scale
of Prodromal Syndromes (SOPS) in Turkish adolescents, ii) to explore
the factor structure of the SIPS/SOPS in the adolescent population,
especially focusing on those under the age of 15, iii) to generate a brief
version of SIPS (SIPS-B).
Methods: A total of 150 adolescents aged between 12 and 18 years,
were consecutively interviewed using SIPS/SOPS. Patients with psychotic
syndrome (n=20), psychosis risk syndrome (PRS) (n=59), and clinical
controls (CC) (n=71) were included in the study.
Results: Principal component analysis (PCA) yielded three latent factors,
explaining 62.7% of the total variance in the whole clinical sample,
including positive symptom factor, disorganized symptom factor, and
negative symptom factor. The area under curve calculated in ROC
analyses involving PRS and CC supported the four-item form of the
SIPS-B (optimal cut-off=12.5, sensitivity=87%, specificity=80%).
Conclusion: Our study results support the notion that the Turkish
translation of SIPS/SOPS meets the reliability and validity criteria in
Turkish adolescents. The SIPS-B could aid clinicians in their routine
clinical practice to expedite referral procedures.
Keywords: Prodrome, psychosis, reliability, SIPS, Turkish validity