E-ISSN 1309-4866
Araştırma Makalesi
Quality of Life in Patients Under Anticoagulant Therapy Compared to Patients Treated with Antiplatelets?
1 Clinic of Neurology, Bakırköy Psychiatric Training and Research Hospital, İstanbul, Turkey  
2 İstanbul University Cerrahpaşa School of Medicine, Institute of Forensic Sciences, İstanbul, Turkey  
Arch Neuropsychiatry ; : -
DOI: 10.5152/npa.2016.15950
687 kez okundu, 0 kez indirildi

Anahtar Kelimeler: Quality of life, stroke, anticoagulants, antiplatelets

Introduction: Health-related Quality of Life (HRQoL) includes the physical, functional, social and emotional well-being of an individual. The most important and frequently used generic HRQoL assessment is the Short Form-36 (SF-36). The objective of the study was to analyze the HRQoL of patients under chronic use of oral anticoagulants in a specialized stroke unit.


Methods:  126 stroke patients who were followed up in our stroke clinic between April 1, 2014 and June 1, 2014 were included in this cross-sectional study,. The inclusion criteria included only patients whose Rankin score was ‘0’ and were on oral antikoagulant or antiplatelet treatment for  ≥1 year.  The questionnare, SF-36 is used for the study. The patients’ age, gender, comorbidities, medical treatments, modified Rankin Scores, bleeding complications, emergency policlinic  admissions and hospitalization were also noted.


Results:  Seventy-five of them were men. The median age was 55.67± 14.23 year. 77 of the patients were on anticoagulant therapy. Being on treatment of anticoagulation did not influence the domains of HRQoL . All the items presented the lowest scores in female group. The items of General Health, Physical Function and Vitality had the  lowest scores among hypertensive patients. The items of  Physical Function, Role Function, Vitality and Mental Health had significantly lowest scores in diabetic group. Bodily Pain scores were significantly lowest in patients having recurrent stroke attacks. Stroke patients taking more than 3 drugs were found worse QoL scores.


Conclusion: Patients under chronic treatment with oral anticoagulant had no negative perception of QoL when attending an anticoagulation specialized outpatient clinic.

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Son Güncelleme: 29.12.2017