E-ISSN 1309-4866
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ICHD-II’ya göre HaNDL Sendromunun Yorumları Yeterli mi?
1 Çukurova University Faculty of Medicine, Department of Neurology, Adana, Turkey  
2 Çukurova University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Adana, Turkey  
3 Ekrem Tok State Mental Health Hospital, Department of Neurology, Adana, Turkey  
4 Çukurova University Faculty of Medicine, Department of Radiology, Adana, Turkey  
Arch Neuropsychiatry 2014; 51: 178-180
DOI: 10.4274/npa.y6858
344 kez okundu, 181 kez indirildi

Anahtar Kelimeler: HaNDL sendromu, başağrısı, ölçütler, MRI lezyonları

A 33-year-old man was admitted to our emergency department for severe frontal headache followed by a state of consciousness disturbance and right-sided hemiparesis. No previous febrile disease, head trauma, vascular risk factor, and medication for any systemic disease were defined in his history. He had experienced a similar disorder three years ago and had recovered completely. Cerebrospinal fluid (CSF) analysis revealed pleocytosis and electroencephalography (EEG) showed diffuse slow wave activity. Hyperintense foci on T2 and FLAIR sequences representing bilateral cortical ischemia, prominent on the right hemisphere, were seen on MRI. Contrast-enhanced T1 images showed marked leptomeningeal thickening with enhancement. The patient was considered as having CSF lymphocytosis (HaNDL syndrome) due to temporary headache with neurologic deficit and CSF pleocytosis. Diagnostic criteria have been identified for this syndrome according to the International Classification of Headache Disorders, 2nd edition (ICHD-II). According to these criteria, neuroimaging should be normal. Positive neuroimaging findings and impairment of consciousness have been reported in a limited number of HaNDL cases so far. Diversity of neurological signs, duration and distinctness from migraine headache have been described in comment section under the diagnostic criteria. Comments are inadequate in this regard. 

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Son Güncelleme: 29.12.2017