E-ISSN 1309-4866
Research Article
Autism Spectrum Symptoms in Children and Adolescents with Obsessive Compulsive Disorder and their Mothers
1 Nevşehir Devlet Hastanesi Çocuk Psikiyatri Kliniği, Nevşehir, Türkiye  
2 Katip Çelebi Üniversitesi Tıp Fakültesi, Psikiyatri Anabilim Dalı, İzmir, Türkiye  
Arch Neuropsychiatry ; : -
DOI: 10.5152/npa.2017.18138
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Key Words: Autism spectrum disorder, broad autism phenotype, obsessive compulsive disorder

Introduction: Obsessive-compulsive disorder (OCD) affects 1%-3% of children and adolescents. Although a close relation between OCD and autism spectrum disorder (ASD) has been pointed out; subclinic ASD symptoms and the relation between maternal ASD symptoms and subclinc ASD symptoms in OCD have not been evaluated adequately.


Methods: The study group consisted of 38 cases (8-18 years old) diagnosed with OCD. The control group (n=39) comprised patients of other clinics at hospital and was matched for gender and age to the OCD patients. The Kiddie Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version(K-SADS-PL) was used to diagnose OCD and allowed comorbidities. Social Communication Questionnaire (SCQ) was used to evaluate children’s ASD symptoms while Autism Spectrum Quotient (ASQ) was used to evaluate maternal broad autism fenotype.  OCD symptoms in children were evaluated with Children Yale-Brown Obsessive Compulsive Scale-(C-Y-BOCS) and OCD symptoms in mothers were evaluated with Yale-Brown Obsessive Compulsive Scale-(Y-BOCS).


Results: There was no significant difference between sociodemographic data of two groups. When cases and controls were compared with SCQ; all subscales’ scores and total score of SCQ were statistically significant higher in OCD group and also mothers of OCD group had statistically significant higher scores in total score of ASQ and subscales except “imagination”. Also in comparing the grups with Y-BOCS and C-Y-BOCS; OCD group had statistically significant higher scores in these scales.


Conclusion: ASD symptoms are prevelant in cases diagnosed with OCD and ASD symptoms increases with OCD severity. Further studies are needed to examine genetic and enviromental common risk factors between OCD and ASD.

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Latest Update: 29.12.2017