E-ISSN 1309-4866
Case Report
Cavum Vergae, Liability and Steroid Treatment: Manic Episode, Brain Imaging Findings and Clinical Follow-up of a Systemic Lupus Erythematosus Case
1 Dokuz Eylül Üniversitesi Tıp Fakültesi Hastanesi, Erişkin Ruh Sağlığı ve Hastalıkları Anabilim Dalı, İzmir, Türkiye  
2 Cizre Devlet Hastanesi, Erişkin Ruh Sağlığı ve Hastalıkları Anabilim Dalı, Şırnak, Türkiye  
3 Dokuz Eylül Üniversitesi Tıp Fakültesi Hastanesi, İç Hastalıkları Anabilim Dalı Romatoloji Bilim Dalı, İzmir, Türkiye  
Arch Neuropsychiatry ; : -
DOI: 10.5152/npa.2017.18129
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Key Words: Systemic lupus erythematosus, cavum vergae, corticosteroid, manic episode

Systemic lupus erythematosus, referred to as SLE or Lupus, is a chronic and idiopathic autoimmune connective tissue disease that involves several organs and organ systems. SLE may lead to a group of psychiatric manifestations caused by organic or non-organic factors. This group of psychiatric manifestations include delirium, anxiety disorders, cognitive dysfunction, mood disorders and psychosis. As well as it is thought that the most common cause of neuropsychiatric lupus is corticosteroid usage, central nervous system involvement and inflammatory processes have also an important role in development of psychiatric manifestations. In other respects, structural brain abnormalities induce proneness to psychotic and manic symptoms. Along with this proneness, cavum vergae, an anomaly which is closely related to anatomic areas associated with mood regulation, may precipitate manic symptoms. In this case report, we present a manic episode case emerging after delirium, with a 1-year history of SLE which has recently been diagnosed with cavum vergae and discuss the process of infection and the corticosteroid treatment which contributed the proneness effect of structural brain anomaly. 

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