E-ISSN 1309-4866
Research Article
The Comparison of Executive Functions with Healthy Controls in Obsessive Compulsive Disorder and Panic Disorder Patients
1 Medicana International Hastanesi, Psikiyatri Bölümü, İstanbul, Türkiye  
2 Medipol Üniversitesi, İnsan ve Toplum Bilimleri Fakültesi, Psikoloji Bölümü, İstanbul, Türkiye  
3 Sağlık Bakanlığı Marmara Üniversitesi Tıp Fakültesi Eğitim ve Araştırma Hastanesi, Psikiyatri Bölümü, İstanbul, Türkiye  
Arch Neuropsychiatry ; : -
DOI: 10.5152/npa.2016.14872
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Key Words: Obsessive Compulsive Disorder, Panic Disorder, Executive Function, Wisconsin Card Sorting Test, Stroop Test

Introduction: Patients with Obsessive Compulsive Disorder (OCD) have been found impaired  on several cognitive functions such as attention, verbal and visual memory and visua-spatial abilities as well as executive functioning. But, some studies did not show any disturbance in executive functioning in OCD. To date, only a few studies on neuropsychological functioning have been done in Panic Disorder (PD) patients. It can be said that there are still no sufficient study to come to a definite conclusion on executive functioning both in OCD and PD patients. In this study, we aimed to measure executive functions of OCD and PD patients compared to healthy controls.


Methods: Seventeen OCD and 15 PD patients who were diagnosed according to DSM-IV-TR and 26 healthy control subjects were taken to the study. Patients were excluded in case of medication usage, medical illnesses and Axis-I comorbidities. Healthy control group were matched to the patients in terms of age, sex, and education. SCID-I, HAM-D and YBOCS tests were administered to the patients. Trail Making Tests (TMT), Verbal Fluency Tests (Controlled Oral Word Association Test and Categorical Naming), Stroop Test and Wisconsin Card Sorting Test (WCST) were administered to the study groups


Results: According to our results, there is no statistically significant difference between three study groups regarding executive functions. There is also no significant correlation between executive tests’ results and YBOCS scores in OCD group.


Conclusions: The results of the PD group are in line with the literature. The resuls of the OCD group can be explained with lack of medication usage and any comorbidity including depression. Small sample size is the major limitation of our study.

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